Warning On Some Resveratrol Supplement Providers!

Warning, many supplement companies are offering some form of grape complex for sale that claims to contain some resveratrol. The reason for the recent attention was focused on a publication in the journal Nature that demonstrated improved health and survival in mice fed a high-fat diet supplemented with resveratrol, the same flavonoid that has been shown to increase the life span of a variety of organisms, including yeast, worms, flies, fish, and mice. This research tied the beneficial effects of resveratrol to mechanisms that underlie caloric restriction, and showed that such approaches could be used to treat a number of chronic disorders and diseases of aging.

Some of the traditional press reports that accompanied this scientific article generated a fair amount of controversy. This was particularly evident in the resveratrol dose used in the experimental mice and the estimated human-equivalent dose that may be required to exert the same type of biological effects. The Life Extension Foundation, has taken a grape-seed/resveratrol product already being used by health-conscious individuals and shown that the favorable biological effects of resveratrol can be achieved at a dose that is more than 10-fold lower than that used in the most-referenced study (referred to as the Harvard study).

Just recently, Life Extension reported that experimental animal studies conducted by BioMarker Pharmaceuticals were under way using the same grape extract fortified with resveratrol that is currently used by Foundation members. The preliminary data suggested a significant overlap in the favorable pattern of gene expression between the grape extract-fed mice and the calorie-restricted mice. In addition, experimental fruit flies fed grape extract showed improvement in a model of Parkinson’s disease, as well as an extended life span. These findings paved the way for further analysis identifying the specific molecular pathways involved in these effects. Life Extension Institute provides an update to these earlier findings.

For the complete resveratrol report from Life Extension go to: Resveratrol article at LifeExtension.com